Scientific Evidence – The Foundation of Efficacy and Safety
Atopic Dermatitis in Children
Our study confirmed that regular treatment with this specific probiotic mixture significantly decreased pruritus and sleep problems and improved quality of life in highly atopic children with severe atopic dermatitis.
Filipovic I, Ostojic O, Vekovic V, Mihajlovic S, Caminati M, Zivkovic Z. Efficacy of Specially Formulated Combination Three Probiotic Strains with Vitamin D3 and Zn in Children with Atopic Dermatitis. American Journal of Pediatrics. 2023;9(4):186-192.
doi: 10.11648/j.ajp.20230904.11
Fragile X Syndrome (FXS)
This pilot study provides initial evidence that probiotics may modulate structural and functional properties of the GM, with potential links to improved behavioural outcomes in children with FXS.
Protic D, Bascarevic D, Dimitrijevic S, et al. Microbiome modulation and behavioural improvements in children with fragile X syndrome following probiotic intake: A pilot study. Scientific Reports. 2026;16:560.
doi: 10.1038/s41598-025-29896-1
Rheumatoid Arthritis
This randomized controlled trial demonstrates that adjunctive probiotic supplementation alongside conventional DMARD therapy significantly improves clinical outcomes in newly diagnosed rheumatoid arthritis patients over a period of 12 months.
Barac B, Lukovic S, Kojic T, Radnic TZ, Bibic A. Therapeutical efficacy of immunobiotics in patients with newly diagnosed rheumatoid arthritis. Journal of Infection in Developing Countries. 2025;19:1861-1868.
doi: 10.3855/jidc.21182